A new publication for which I am a co-author is out on the application of covariance NMR processing…
Multistep correlations via covariance processing of COSY/GCOSY spectra: opportunities and artifacts
Long-range homonuclear coupling pathways can be observed in COSY or GCOSY spectra by the acquisition of spectra with larger numbers of increments of the evolution period, t1, than would normally be used. Alternatively, covariance processing of COSY-type spectra acquired with modest numbers of t1 increments, allows the observation of multistage correlations. In this work results obtained from covariance-processed GCOSY spectra are fully analyzed and compared to normally processed COSY and 80 ms TOCSY spectra.
